个人简介

工作经历

2026.01-至今            william威廉中文,副教授

2022.08-2026.01      william威廉中文,助理教授

2020.08-2022.07      北京大学基础医学院病原生物学系,博士后

教育经历

2017.09-2020.07      北京大学      病原生物学      医学博士

2015.09-2017.07      哈尔滨医科大学      病原生物学      医学硕士

2010.09-2015.07      哈尔滨医科大学      基础医学(七年制)      医学学士

 

学术成果

代表性成果(*代表共同第一作者,#代表共同通讯作者)

  1. Huang H*, Shi W*, Yan H*, Fan L, Lu J, Long Z, Li X, Li J, Wang J#, Liu L#, Qian J#. Dual roles of CXCR4 (C-X-C motif chemokine receptor 4) in promoting entry of ebolavirus and targeting excessive glycoprotein for reticulophagic degradation to facilitate viral fitness. Autophagy. 2025, 21(10):2148-2167. (共同一作排第一,中科院一区TOP,IF 14.3)

     

  2. Li Z*, Song Y*, Huang H*, Chen R, Liu M, Yang X, Luo Z, Liu BM, Wang J. Highly stable Cas9 promotes HBV genome destruction by antagonizing HSC70-mediated degradation. Emerging Microbes & Infections. 2025, 14(1):2556728.(共同一作排第三,中科院一区TOP,IF 7.5)

     

  3. Gu Z*, Jiang Q*, Abulaiti A*, Chen X*, Li M, Gao N, Guan G, Zhang T, Yang D, Xi J, Yu G, Liu S, Zhu Z, Gao Z, Zhao J, Huang H#, Chen X#, Lu F#. Hepatitis B virus enhancer 1 activates preS1 and preS2 promoters of integrated HBV DNA impairing HBsAg secretion. JHEP reports. 2024, 6(9):101144. (共同通讯排第三,中科院一区TOP,IF 7.5)

     

  4. Fan L*, Wang Y*, Huang H*, Wang Z, Liang C, Yang X, Ye P, Lin J, Shi W, Zhou Y, Yan H, Long Z, Wang Z#, Liu L#, Qian J#. RNA binding motif 4 inhibits the replication of ebolavirus by directly targeting 3'-leader region of genomic RNA. Emerging Microbes & Infections. 2024, 13(1):2300762.(共同一作排第三,中科院一区TOP,IF 7.5)

     

  5. Abulaiti A*, Gu Z*, Jiang Q, Huang H#, Lu F#. Letter to the Editor: Low sensitivity of RT-Alu-PCR in detection of HBV-integrated chimeric transcripts. Hepatology. 2023, 77(2):E19-E20. (共同通讯排第二,中科院一区TOP,IF 16.8)

     

  6. Huang H*, Yuan D*, Li M, Abulaiti A, Lu F. Active HBV replication in hypoxic pericentral zone 3 is upregulated by multiple host factors including HIF-1a. Journal of Hepatology. 2022, 77(1):265-267. (共同一作排第一,中科院一区TOP,IF 33.0)

     

  7. Huang H*, Han Q*, Zheng H, Liu M, Shi S, Zhang T, Yang X, Li Z, Xu Q, Guo H#, Lu F, Wang J#. MAP4K4 mediates the SOX6-induced autophagy and reduces the chemosensitivity of cervical cancer. Cell Death & Disease. 2021, 13(1):13. (共同一作排第一,中科院一区TOP,IF 9.6)

     

  8. Chen R*, Huang H*, Liu H, Xi J, Ning J, Zeng W, Shen C, Zhang T, Yu G, Xu Q, Chen X, Wang J#, Lu F#. Friend or foe? Evidence indicates endogenous exosomes can deliver functional gRNA and Cas9 protein. Small. 2019,15(38):e1902686.(共同一作排第二,中科院二区TOP,IF 12.1)

     

  9. Huang H*, Wang J*, Li W, Chen R, Chen X, Zhang F, Xu D, Lu F. Serum HBV DNA plus RNA shows superiority in reflecting the activity of intrahepatic cccDNA in treatment-naive HBV infected individuals. Journal of Clinical Virology. 2018, 99-100:71-78. DOI: 10.1016/j.jcv.2017.12.016.

 

获批专利

  1. 钱军,黄鸿鑫,卢伽俊,石雯迪,晏辉钧。ZL202510471381.X(第二发明人)
  2. 钱军,黄鸿鑫,石雯迪,刘林娜,晏辉钧。ZL202410405576.X(第二发明人)
  3. 鲁凤民,顾智强,黄鸿鑫,陈香梅,姚明解。ZL202211143953.4.(第三发明人)

 

科研项目

  1. 国家自然科学基金委员会,青年科学基金项目(C类),2022.01~2023.12。
  2. 广州市科技局,基础研究计划,基础与应用基础研究专题青年博士“启航项目”,2024.01~2025.12。
  3. 广东省科技计划项目,2024.01~2026.12。

 

ORCID: https://orcid.org/0000-0001-5449-1675

 

科研之友主页:https://www.scholarmate.com/apps/p/gPRAsV